Customer reviews · Copper Peptide Serum
Average rating on Amazon
Reviews shown here are copied from our Amazon listing. Some reviewers received the product free through Amazon Vine, Amazon’s program for honest early reviews.
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Rafael
Verified purchase
September 21, 2026
Impressive Copper Peptide Serum
I am impressed with this copper peptide serum. It works exactly as advertised and gives my skin a smoother and more refreshed texture. The formula absorbs quickly and does not leave any greasy residue. Considering the affordable price, I was not expecting such a high-quality product, but it performs as well as some much more expensive serums I have tried.
Hassam Usmani
Verified purchase
September 7, 2026
My best buy
My skin feels firmer and looks so much smoother after 2 weeks. No irritation and absorbs really well
Juan Garcia
Amazon review
September 29, 2026
Solid peptide-packed serum that lightweight and layers easily
I was interested to try this copper peptide serum because it combines GHK-Cu with Argireline, Matrixyl 3000, Hyaluronic Acid, and a Ceramide Complex all into a single formula. These particular ingredients are marketed to improve the effectiveness of the serum. Combining these targeted ingredients helps streamline my daily skincare routine and saves me from applying multiple separate serums. These ingredients are marketed to help support skin firmness, hydration, and the moisture barrier. I haven't experienced any negative reactions or issues while using it.
The serum has a smooth, liquid texture that goes on easily and absorbs quickly without leaving a sticky or greasy residue. It’s fragrance-free, so there's no noticeable scent or heavy perfume to worry about. Over the duration of using this for the past few weeks, I’ve had no skin irritation, redness, or major breakouts. In terms of overall hydration, my skin has felt smooth and well-moisturized throughout the day.
The 1 oz dropper bottle makes dispensing just a few drops easy, and a little goes a long way. Knowing it includes barrier-supporting ceramides alongside hyaluronic acid gives me peace of mind about my skin barrier health. It offers great value for money and is competitively priced compared to similar multi-peptide serums on Amazon, making it a solid choice—especially if you catch it on sale or with a coupon.
Sarah
Amazon review
August 26, 2026
Clearer skin after 10 days, niacinamide, copper peptides and more, not irritating to skin
I have been using this serum for 10 days now, and am very happy with the early results. I have heard about copper peptides and wanted to try them, but hadn’t before this. The first thing I noticed about the serum is the color, a pretty blue, which is normal and a good thing in a copper peptide serum as the peptides are blue. While copper peptides can take 8 weeks to 6 months to show the full potential of improvements to the skin, this formula has lots of other beneficial ingredients. What I am noticing is the my skin seems clearer, free of blemishes and irritations. I do have mild rosacea and this not only has not irritated it, it actually seems to be calming my skin. As this formula is not acidic or exfoliating, I use an acid based toner or treatment as needed to keep my skin smooth, which complements the effects of this serum beautifully without over-exfoliating. I love serums that are non-irritating beacuse I do like to combine products but have sensitive skin, so doubling up on acids is a no-no for me. The original price on this was pretty pricey for 1 oz. , but it is on sale right now and I am considering buying another bottle so I can use long enough to see the best results. The product is made in China as another reviewer notes. I try out many beauty products and in my exoerience there are both good and not-so-good products from China. So far this seems to be oneof the good ones. I like these ingredients and am seeing nice initial results from the serum such as clearer, softer and more moisturized skin. Seeing these initial results motivates me to keep up the daily use of this, as I am excited to see what happens at 6-8 weeks, when the copper peptide remodeling effects start to show. Looks like I have about 30 days left in this bottle based on what I’ve used so far, so guess I may need to hop on this sale price and pick up a second one.
dusksi
Amazon review
September 22, 2026
POISELLE Copper Peptides Serum for Face
As I get older I've noticed my skin needs different moisturizers than just whatever I buy off the shelf. I saw this one, and the peptides intrigued me so I decided to give it a try. So far it seems to be working well. I've been using it daily for almost a month. My skin doesn't feel greasy, this absorbs well into it. I feel like my skin has been looking softer and plumper. Obviously it hasn't been that long yet, but I plan to continue using this and would consider buying it again. It was $39.99 when I ordered it, but I see it listed for $14.99 when I write this review. It's definitely a good deal and worth trying at the latter price
Worldgroup SysOp
Amazon review
September 7, 2026
Impressive Combination of Peptides in One Serum
I have tried quite a few facial serums, and what caught my attention with this one was the combination of GHK Cu copper peptides, Matrixyl 3000, Argireline, and hyaluronic acid. It packs several ingredients I look for into one product.
After using it for over a month, the serum has a nice consistency and spreads easily across my face. A small amount covers quite a bit of skin, so the one ounce bottle should last a reasonable amount of time. It absorbs nicely and does not leave my face feeling excessively greasy or sticky. I feel that it is effective.
After applying it, my skin feels hydrated, soft, and smooth. I have also been able to use it as part of my regular skin care routine without experiencing irritation.
I think claims involving wrinkles, firmness, and other signs of aging need more time to evaluate. I would not expect any serum to produce dramatic changes overnight, but I like how my skin looks and feels while using this one.
Overall, I am impressed with the ingredient combination and how pleasant the serum is to use. It feels like a quality skin care product, and I am interested to see what consistent use does over the next several weeks.
Amazon Customer
Amazon review
August 19, 2026
Great serum packed with a lot of skin benefiting ingredients!
This is my first time trying this skincare brand Poiselle. I love incorporating peptides and ceramides into my skincare. This serum packs a lot into its formula to really help with different areas of the skin. From hydration, skin barrier, anti-aging and firmness to conditioning the skin as well. This is also my first time trying a product with a copper peptide and Matrixyl 3000. Honestly I’ve been really liking the results so far. The serum is a cool blue color and a few drops goes a long way. I know the bottle is quite small but if you only use a few drops, it should last quite awhile. There is a bit of a chemical scent to it, but nothing too overpowering. The scent also dissipates quite quickly as well. My skin feels really hydrated and refreshed after using this. I haven’t noticed much firmness to my skin just yet but that’ll take some time. I have fairly sensitive skin and i haven’t had any issues with irritation or break outs at all. I’m definitely going to keep using this serum as i love how hydrating it is and gives my skin a nice dewy glow. This product is quite expensive, but it currently has a 40% off coupon which brings the price down a lot. I definitely think it’s worth it if you can grab this while it’s on sale.
Ashley
Amazon review
September 25, 2026
So far so good
I ordered this because I love matrixyl and have been using it for years.
I work from home and keep this at my desk because my job gives me frequent reminders why moisturizing is important.
It has only been a few weeks, so I can't fully speak to how effective it is. What I can say is that it absorbs well, my skin really seems to drink it in quickly. It leaves my skin feeling soft, and not greasy or sticky. I've noticed that it doesn't even pill - which is nice.
And I like the price. I think it's a decent value if you're looking to add something a little extra to your routine.
Trying Stuff Since 2022
Amazon review
September 9, 2026
Hydrating Serum That Fits Easily Into My Routine
I have been using this serum for more than a month, and I like how simple it is to work into my regular skincare routine. The formula combines copper peptides, Matrixyl 3000, Argireline, and hyaluronic acid, so it brings together several ingredients people commonly look for in an anti-aging serum.
The texture is light, spreads evenly, and absorbs without leaving my skin greasy or tacky. A little goes a long way, and my skin feels soft, smooth, and hydrated after applying it. I have not experienced irritation while using it.
I think it takes longer-term use to judge claims about fine lines and firmness, so I would not expect dramatic overnight changes. But based on the pleasant feel, hydration, and ingredient blend, this has been a solid addition to my skincare routine.
Amazon Customer
Amazon review
September 3, 2026
Copper Peptide Serum
I've been adding this to my skincare routine for a couple weeks now and have been pretty happy with the results. I have perimenopausal skin that has started to show signs of aging and losing elasticity. I really like this serum for a few reasons. It is gentle and hydrating, absorbs very quickly, and is very light-weight. I feel like adding products to my skincare routine can be difficult because there is only so much I can put on my face before it feels weighted down under a layer of product, so I was really happy about the extreme weightlessness of this serum. Even when I use it by itself, my skin feels firmer and plumper, without any dryness. The bottle seems to be lasting a long time, since I only use a few drops a day, so I feel it is a good value for the benefits.
T-Rock
Amazon review
September 1, 2026
Effective peptide serum with great texture and ingredients
I’ve had good success with Korean skincare products, especially anything with Hyaluronic Acid, so I was glad to see it included here. This blue copper peptide serum spreads smoothly over my face and absorbs well without feeling sticky or heavy. The texture is excellent — easy to apply and works nicely under moisturizer.
The formula includes GHK‑Cu copper peptides, which are known for helping with fine lines, firmness, and overall skin tightness over time. Based on my experience with peptides, this should continue improving my skin as I use it consistently. The ingredient list is strong overall, with multiple peptides and hydrating components that work well for me.
Considering the quality of the formula and how well it applies, this is a great deal for an effective anti‑aging serum. I’m looking forward to seeing the long‑term benefits.
Abee Ward
Amazon review
September 4, 2026
Great serum, even for sensitive skin
I found this serum very effective at reducing the lines on my forehead and it's half the price of other copper serums. It's lightweight, non greasy and doesnt cause breakouts on my sensitive skin. I like that it can go under sunscreen or moisturizer without peeling. I definitely think it's made my skintone appear more radiant and gives a nice glow.
LCB
Amazon review
August 16, 2026
Packed serum
I really like how lightweight this Poiselle copper peptide serum feels. It absorbs quickly without leaving my skin greasy or sticky, and it gives my skin a nice boost of hydration. It is a 1floz dropper bottle that contains a combination of peptides, hyaluronic acid, ceramides, and copper peptides including 1.5% GHK-Cu, 3% Matrixyl 3000, and 5% Argiriline. Easy to add to my morning or nighttime routine, and my skin feels smooth and comfortable after using it. I've had no adverse skin reactions using it.
Lilly Sky
Amazon review
August 19, 2026
This serum has been fantastic for keeping my skin hydrated and looking smoother!
This serum has been fantastic for supporting my skin hydration and appearance. I really like the lightweight texture because it absorbs quickly without making my face feel greasy or heavy.
The formula says that it includes 1.5% GHK Cu copper peptides, 3% Matrixyl 3000, 5% Argireline, hyaluronic acid, and a ceramide complex. I like having several skincare ingredients focused on hydration and maintaining a smoother looking complexion in one product.
My skin feels softer and more comfortable after using it, and I have been happy with the refreshed, hydrated appearance. With regular use, my complexion has been looking smoother and healthier.
The fragrance free formula is another plus for me, and the dropper makes it easy to dispense the right amount. It also layers nicely with the rest of my skincare without feeling heavy. Highly recommended!
ZuLaNi
Amazon review
October 2, 2026
Good
Professional appearance. The dropper makes it easy to dispense a small amount at a time. The bottle feels like good quality and is easy to incorporate into a skincare routine. Nice presentation and reasonable value for this type of serum. I don’t notice a strong fragrance. Ingredients seem good. Didn’t note anything alarming that I’m aware of. Not sure about effectiveness as I haven’t used it consistently enough.
Sarah Stewart
Amazon review
September 21, 2026
lightweight texture, skin doesn't feel greasy after use
I've been enjoying this copper peptide serum as part of my skincare routine. It has a lightweight texture that absorbs easily without leaving my skin feeling greasy or sticky. My skin feels soft and hydrated after applying it, and I like that it contains several peptides for added skincare benefits. The 1-ounce bottle is a convenient size. Overall, a nice addition to my daily skincare routine.
Cheesasaurus Rex
Amazon review
August 22, 2026
Hydrating Peptide Serum That Makes Skin Feel Smoother
I’ve been really enjoying this serum as part of my morning and evening skincare routine. The texture is lightweight and absorbs quickly without leaving my skin sticky or greasy, which makes it easy to layer underneath moisturizer and other products. I only need a few drops for my entire face and neck, so the 1 oz bottle should have pretty good longevity.
The biggest difference I’ve noticed is in hydration and overall skin texture. My skin feels softer, smoother, and more supple after using it consistently, and it gives my complexion a healthy, refreshed look. It also seems to help my skin look a little more plump, which makes fine lines appear less noticeable. I like that it combines copper peptides, Matrixyl 3000, Argireline, hyaluronic acid, and ceramides rather than relying on just one type of ingredient.
It’s also been easy to use consistently because it doesn’t pill or feel heavy, and I can comfortably use it both morning and night. The effects are more noticeable with regular use rather than being an overnight transformation, but the hydration and smoother feel are something I can appreciate pretty quickly.
Overall, this is a nice peptide serum for anyone looking for lightweight hydration and a smoother, healthier-looking complexion. A little goes a long way, so I expect the bottle to last a decent amount of time with 2–3 drops per application.
Level Up
Amazon review
September 12, 2026
Moisturizing
The Cooper Peptides serum was very moisturizing. The first two ingredients is water and hyaluronic acid. I definitely could feel the hyaluronic acid at work as it drawled in moisture and locked it in. I saw the instance effect of my face being moisturized and awaken. It did not interfered with my AHAs or retinal. I can use it both in the morning and at nights. Sometimes when I get home from work and wash my face, it’s the only thing I put on my skin because it’s so moisturizing. It’s usually my base or the item I put on immediately after putting on my exosome shot. It’s a thin blue-tinted serum that immediately absorbs into the skin. It helps to diminish some discoloration such as I see a change in my dark circles in which they look lighter right after applying. This is a temporary effect which my research and copper peptides are known to do this, it’s not a long term effect. Overall, I like the product and will start incorporating it in my daily morning and night routine. It is also priced reasonable.
K
Amazon review
September 2, 2026
Nice and moisturizing
Good face serum.
My only complaint is that this is made in China, not a Korean product.
I'd say its effective at making my skin feel nice and hydrated.
The product comes with a dropper so application is really easy, it has a slight blue tint.
So far there has not been any irritation.
Its a decent reasonable price though I wish it wasn't made in china.
C.A.H.
Amazon review
August 29, 2026
Good for aging skin
I've been using this serum for a few weeks now. No complaints: it absorbs and is well tolerated by my sensitive skin. The ingredients are ones that I recognize from other, high quality skin care products, which is why it isn't cheap. Copper peptides can really turn your skin around, according to my esthetician. I believe her, because using them myself is really when I began to see a difference in my aging skin. The color is more even and the texture, just better. I recommend!
SonomaGal
Amazon review
August 18, 2026
Feels soothing and nourishing
Poiselle’s “Korean inspired” Copper Peptides Serum has a soothing, nourishing and somewhat luxurious feel on the face, but it will take some time to know if it can really deliver “fine line reduction.” Even if it doesn’t, the serum provides good hydration; it’s non-oily and packed with ingredients that promise to refresh and improve skin appearance. The serum contains a copper peptide formula along with facial-skin stalwarts such Hyaluronic Acid, a Ceramide Complex, and more.
I do think the 1 fluid ounce bottle is a bit pricey, but that might have something to do with tariffs. The Poiselle Company is based in Wyoming. Its copper peptide serum, according to the bottle and outer box. is made in China from “globally sourced ingredients.”
Lance C.
Amazon review
August 21, 2026
Has a slight effect, so far.
The product appears to have a slight positive effect, short term so far, it has no noticeable side effects, easy to apply, no odd smell.
Real Reviews
Copper Peptide Serum · from AmazonImpressive Copper Peptide SerumRafaelVerified purchase
My best buyHassam UsmaniVerified purchase
Solid peptide-packed serum that lightweight and layers easilyJuan GarciaAmazon review
Clearer skin after 10 days, niacinamide, copper peptides and more, not irritating to skinSarahAmazon review
POISELLE Copper Peptides Serum for FacedusksiAmazon review
Impressive Combination of Peptides in One SerumWorldgroup SysOpAmazon review
Great serum packed with a lot of skin benefiting ingredients!Amazon CustomerAmazon review
So far so goodAshleyAmazon review
Hydrating Serum That Fits Easily Into My RoutineTrying Stuff Since 2022Amazon review
Copper Peptide SerumAmazon CustomerAmazon review
Effective peptide serum with great texture and ingredientsT-RockAmazon review
Great serum, even for sensitive skinAbee WardAmazon review
Packed serumLCBAmazon review
This serum has been fantastic for keeping my skin hydrated and looking smoother!Lilly SkyAmazon review
GoodZuLaNiAmazon review
lightweight texture, skin doesn't feel greasy after useSarah StewartAmazon review
Hydrating Peptide Serum That Makes Skin Feel SmootherCheesasaurus RexAmazon review
MoisturizingLevel UpAmazon review
Nice and moisturizingKAmazon review
Good for aging skinC.A.H.Amazon review
Feels soothing and nourishingSonomaGalAmazon review
Has a slight effect, so far.Lance C.Amazon review
Reviews from our Amazon listing. Some reviewers received the product free through Amazon Vine.